Program
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Day 1 2024/5/30 Thur.
9:00-
1. Introduction
Jun Natsume(Nagoya University Graduate School of Medicine, Nagoya, Japan)
9:10–10:20
2. Basic Mechanism of Febrile Seizures
| Chair: | Mitsumasa Fukuda | (Tokyo Metropolitan Neurological Hospital, Tokyo, Japan) |
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9:10-10:00
| Tallie Z. Baram | (University of California, Irvine, CA, USA) |
| Mechanisms and outcomes of febrile seizures and febrile status epilepticus | |
10:00-10:20
| Ryuta Koyama | (National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan) |
| Non-apoptotic caspase-3 activation drives microglial synaptic phagocytosis after experimental febrile seizures | |
10:30-11:50
3. Genetics
| Chair: | Masanori Takeoka | (Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA) |
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10:30-11:20
| Ingrid Scheffer | (University of Melbourne, Austin and Royal Children’s Hospital, Florey Institute and Murdoch Children’s Research Institute, Melbourne, Australia) |
| Developmental and Epileptic Encephalopathies | |
11:20-11:50
| Norimichi Higurashi | (Musashi-Kosugi Pediatrics & Epilepsy Clinic, Tokyo, Japan) |
| Dravet syndrome pathogenesisーnovel insights from Scn1a knockout rat research | |
12:00-13:00
Luncheon Seminar 1
| Chair: | Toru Okanishi | (Division of Child Neurology, Faculty of Medicine, Tottori University, Tottori, Japan) |
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| Hiroki Nariai | (Department of Pediatrics, University of California, Los Angeles, CA, USA) |
| When Fever Meets Medication-Resistant Focal Epilepsy: Navigating the Role of Pediatric Epileptologists in the United States | |
13:10-14:30
4. General Managements and Clinical Aspects of Febrile Seizures
| Chair: | Masaya Kubota | (Shimada Ryoiku Medical Center for Challenged Children, Tokyo, Japan) |
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13:10-13:30
| Mitsuru Kashiwagi | (Department of Pediatrics, Hirakata City Hospital, Osaka, Japan) |
| Clinical characteristics associated with febrile seizure incidence in COVID-19 | |
13:30-13:50
| Masanori Takeoka | (Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA) |
| Clinical Management of Seizures with Fever in USA | |
13:50-14:10
| Sanem Yılmaz | (Ege University Medical faculty, İzmir, Turkey) |
| Approaching febrile seizures: diverse perspectives across different countries | |
14:10-14:30
| Indra Sahri | (Department of Child Health, Medical School, Padjadjaran University, Dr Hasan Sadikin Hospital, Bandung, Indonesia) |
| Descriptive study of febrile seizure in focal epilepsy patient in Hasan Sadkin Hospital, Bandung | |
14:40-15:40
5. Clinical aspects of Dravet Syndrome and PCDH19 Clustering Epilepsy
| Chair: | Hideaki Shiraishi | (Department of Pediatrics, Dokkyo Medical University School of Medicine, Tochigi, Japan) |
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14:40-15:00
| Takeshi Suzuki | (Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan) |
| Effect of levodopa on pathological gait in Dravet syndrome: A randomized crossover trial using three-dimensional gait analysis | |
15:00-15:20
| ByungChan Lim | (Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Children’s Hospital, Seoul, South Korea) |
| Differential diagnosis of Dravet syndrome at its seizure onset | |
15:20-15:40
| Kenneth Myers | (Research Institute of the McGill University Health Centre, Montreal, Canada) |
| Ictal Asystole in PCDH19-Related Epilepsy | |
17:30-19:00
Poster Session
19:00-20:00
6. Special lecture (sponsored by Nippon Shinyaku Co.,Ltd.)
| Chair: | Jun Natsume | (Nagoya University Graduate School of Medicine, Nagoya, Japan) |
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| Charlotte Dravet | (Honorary consultant, Policlinico A.Gemelli, Università Cattolica del Sacro Cuore, Roma, Italy) (Web lecture) |
| Dravet syndrome, from one century to another one | |
Day 2 2024/5/31 Fri.
8:00-9:30
7. Febrile Illness and Neurometabolic Disorders
| Chair: | Masakazu Mimaki | (Department of Pediatrics, Teikyo University School of Medicine, Tokyo, Japan) |
|---|---|---|
| Tokiko Fukuda | (Department of Hamamatsu Child Health and Development, Hamamatsu University School of Medicine, Hamamatsu, Japan) |
8:00-8:50
| Phillip PEARL | (Department of Neurology, Boston Children’s Hospital, Harvard Medical School, Boston, MA USA) |
| Metabolic Epilepsy: New Diagnosis and Treatment in the Genetic Era | |
8:50-9:10
| Shyi-Jou Chen | (Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan, Department of Microbiology and Immunology, National Defense Medical center, Taipei, Taiwan) |
| The regulation of chemotaxis in CNS microenvironment in experimental autoimmune encephalomyelitis | |
9:10-9:30
| Asuri Narayan Prasad | (Western University, Ontario, ON, Canada) |
| Linking Febrile and Afebrile Seizures to Pyridoxine Responsiveness: A Treatable Epilepsy or a Hydra-headed Beast. | |
9:35-10:15
8. EEG for febrile seizures: Debate
| Chair: | Katsuhiro Kobayashi | (Asahigawaso Rehabilitation and Medical Center, Okayama, Japan) |
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9:35-9:55
| Noboru Yoshida | (Koto Hospital, Tokyo, Japan) |
| Is interictal EEG helpful for febrile seizures? - cons: not really indicates sequelae | |
9:55-10:15
| Hideaki Kanemura | (Department of Pediatrics, Toho University Medical Center Sakura Hospital, Chiba, Japan) |
| Is interictal EEG helpful for febrile seizures? -pros: prediction about subsequent epilepsy | |
10:20-12:00
9. Febrile Status Epilepticus
| Chair: | Kenjiro Kikuchi | (Division of Neurology, Saitama Children's Medical center, Saitama, Japan) |
|---|---|---|
| Kuriko Shimono | (United Graduate School of Child Development, Osaka University, Osaka, Japan) |
10:20-10:50
| Raman Sankar | (University of California, Los Angeles, CA USA) |
| Pathophysiology of Self-Sustaining Seizures with Emphasis on Febrile Status Epilepticus | |
10:50-11:40
| Douglas Nordli | (University of Chicago, Chicago, IL USA)(Web lecture) |
| Development of epilepsy and the associated EEG findings from the FEBSTAT study | |
11:40-12:00
| Jun Natsume | (Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan) |
| A hippocampal diffusion abnormality after febrile status epilepticus is related to subsequent epilepsy | |
12:10-13:00
Luncheon Seminar 2 (sponsored by Takeda Pharmaceutical Company Limited, Japan Medical Office)
| Chair: | Mitsuhiro Kato | (Showa University, Tokyo, Japan) |
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| Vicente Villanueva | (University and Polytechnic La Fe Hospital, Valencia, Spain.) |
| Quality of life of pediatric epilepsy: Focus on Dravet and Lennox-Gastaut syndrome | |
13:20-14:50
10. Acute Encephalopathies
| Chair: | Masashi Mizuguchi | (National Rehabilitation Center for Children with Disabilities, Tokyo, Japan) |
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13:20-13:50
| Jun-ichi Takanashi | (Tokyo Women's Medical University Yachiyo Medical Center, Tokyo, Japan) |
| Acute infectious encephalopathy in Japan, focusing on AESD and encephalopathy associated with COVID-19 | |
13:50-14:20
| Choong Yi Fong | (Senior Consultant Paediatric Neurologist, University Malaya, Kuala Lumpur, Malaya) |
| Approach and recognition of Infection-Triggered Encephalopathy Syndromes (ITES) | |
14:20-14:50
| Terrence Thomas | (KK Women’s and Children’s Hospital, Singapore) |
| Treatments and interventions in the Infection-Triggered Encephalopathy Syndromes (ITES) | |
15:00-16:10
11. FIRES (febrile infection-related epilepsy syndrome)
| Chair: | Hiroshi Sakuma | (Department of Brain & Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) |
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15:00-15:20
| Ichiro Kuki (Department of Pediatric Neurology, Osaka City General Hospital, Osaka, Japan) | |
| Intrathecal dexamethasone therapy and epilepsy surgery to treat febrile infection-related epilepsy syndrome | |
15:20-16:10
| Ronny Wickstr_m | (Karolinska Institutet, Stockholm, Sweden) |
| Febrile Infection-Related Epilepsy Syndrome (FIRES) in Children: Current concepts, Diagnosis and Management | |
16:10-
Closing Remarks
| Jun Natsume | (Nagoya University Graduate School of Medicine, Nagoya, Japan) |
| Choong Yi Fong | (University of Malaya, Kuala Lumpur, Malaysia) |
17:30-19:00
Poster Session
19:30-
Welcome Party (Crowne Plaza - ANA Hotel Grand Court Nagoya)
Day 3 2024/6/1 Sat.
10:10-11:40
Joint Symposium of Infantile Seizure Society and Japanese Society of Child Neurology
“Developmental and Epileptic Encephalopathies”
| Chair: | Raman Sankar |
|---|---|
| Hideo Yamanouchi |
| Speakers: | Ingrid Scheffer |
|---|---|
| Lee Wang-Tso | |
| Yuji Ito | |
| Ryoko Honda |



